Russian study for stem cell in SCI injuary

[كساندرا]

Russian study for stem cell transplantation
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The minimally manipulated stem cells were subarachnoidally implanted into 15 patients (18-52 years old) with severe consequences of traumatic spinal cord injury at cervical or thoracic spine level. The times after spinal cord injury were from 1 month to 6 years. Each patient underwent from one to four stem cell transplantations (CT) with various time intervals.
In 11 of 15 cases, stem cell transplantation was combined with an operative partial disruption of a connective tissue cyst and with implantation into a spinal cord lesion of a spinal cord fragment together with olfactory ensheathing cells. Before a stem cell treatment the patients showed complete motor and sensory function disorder consistent with a grade A of spinal cord injury according to Frankel classification. With stem cell treatment, six patients improved their neurological status from A to C grade of spinal cord injury, exhibiting incomplete restoration of both motor and sensory function.
The status of other five CT-treated patients became consistent with spinal cord injury grade B and was characterized by appearance of contracting activity in some muscles and incomplete restoration of sensitivity. The remaining four patients did not exhibit any clinical improvements. No serious complications of a stem cell transplantation treatment were noted.
The results suggest a clinical relevance of the stem cell treatment based on a cell transplantation to treating severe consequences of a spinal cord injury.